The John Paul II Sanctuary in Kraków Łagiewniki is one of the youngest centres of its kind in Poland. Cardinal Stanisław Dziwisz inaugurated it in 2011 as part of the John Paul II Centre ‘Do not be afraid’. 2011 also marked the beginning of the official veneration of the Polish Pope at this very site. The sanctuary consists of a lower church and an upper church. Mass is celebrated on weekdays in the former (the Church of the Relics), while in the latter, mass is celebrated on Sundays and public holidays. Relics are kept in the sanctuary. These are: the blood of the Polish Pope, enclosed in a glass casket placed inside the marble altar; the cassock worn by Saint John Paul II when an assassin attempted to take his life on 13 May 1981, which is in a glass case in the upper church; the papal pastoral cross, and the chasuble with mitre. It also features the cross in front of which the Pope prayed in his private chapel during the last Stations of the Cross in his lifetime at Rome's Colosseum in 2005. Also displayed in the Chapel of the Chaplaincy is a slab from John Paul II's tomb from the Vatican Grottoes of St Peter's Basilica in Rome.

The sanctuary was solemnly consecrated on 16 October 2016, the 38th anniversary of the election of Cardinal Karol Wojtyła as Pope. In addition to the sanctuary itself, other attractions are worth a visit, including the exhibition of copies of the Turin Shroud, which tells the story of the Shroud's creation and presents the latest scientific evidence of the canvas's authenticity. Also noteworthy is the museum, which houses memorabilia and personal items belonging to the Pope during his lifetime, donated to him during his pilgrimages around the world.